Erythropoietin Attenuates Cardiac Dysfunction in Experimental Sepsis via Activation of the β-Common Receptor Running title: EPO reduces septic cardiac dysfunction via the βcR
نویسندگان
چکیده
Areeg I. Khan, Sina M. Coldewey, Nimesh S.A. Patel, Mara Rogazzo, Massimo Collino, Muhammed M. Yaqoob, Peter Radermacher, Amar Kapoor, Christoph Thiemermann Centre for Translational Medicine and Therapeutics, Queen Mary University of London, Barts and The London School of Medicine & Dentistry, The William Harvey Research Institute, London, United Kingdom; Department of Anesthesia and Intensive Care Medicine, Hannover Medical School, Hannover, Germany; Department of Drug Science and Technology, University of Turin, Turin, Italy; Department of Nephrology, Barts Health NHS Trust, The Royal London Hospital, London, United Kingdom; Division of Pathophysiology and Process Development, Department of Anesthesiology, University Hospital, Ulm, Germany.
منابع مشابه
Erythropoietin attenuates cardiac dysfunction in experimental sepsis in mice via activation of the β-common receptor
There is limited evidence that the tissue-protective effects of erythropoietin are mediated by a heterocomplex of the erythropoietin receptor and the β-common receptor ('tissue-protective receptor'), which is pharmacologically distinct from the 'classical' erythropoietin receptor homodimer that is responsible for erythropoiesis. However, the role of the β-common receptor and/or erythropoietin i...
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